SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04160

Signal sequence   MASLAALLPLLALLVLCRLDPAQA

Length  24

Organism  Oryctolagus cuniculus (Rabbit)

UniProt ID  P01311,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04160.cif

Structure  SPKB04160.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2477.10504

Aliphatic index  183.3333333

Isoelectric point  6.161167719

Charge (pH=7)   -0.063547244

Topological polar surface area  877.56

Aromaticity  0

Average rotatable bonds  3.25

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -3.56993

Hydropathy 



Literature Information


Title  Species variation in the amino acid sequence of insulin.

DOI  10.1016/0002-9343(66)90145-8,

Publication Year  1966

PubMed ID  5949593,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.