SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04153

Signal sequence   MKSVQFCFLFCCWRAICCR

Length  19

Organism  Ovis aries (Sheep)

UniProt ID  P01227,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04153.cif

Structure  SPKB04153.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2344.93304

Aliphatic index  61.57894737

Isoelectric point  8.515071998

Charge (pH=7)   2.687809063

Topological polar surface area  816.05

Aromaticity  0.210526316

Average rotatable bonds  3.894736842

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  31

X logP energy  -4.33966

Hydropathy 



Literature Information


Title  Primary structure of the ovine pituitary follitropin beta-subunit.

DOI  10.1042/bj1970541,

Publication Year  1981

PubMed ID  6798969,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.