SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04152

Signal sequence   MTAIFLMSMLFGLACGQAMS

Length  20

Organism  Sus scrofa (Pig)

UniProt ID  P01224,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04152.cif

Structure  SPKB04152.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2123.64764

Aliphatic index  93

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  720

Aromaticity  0.1

Average rotatable bonds  3.5

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  30

X logP energy  -4.8251

Hydropathy 



Literature Information


Title  Porcine thyrotropin. The amino-acid sequence of the alpha and beta subunits.

DOI  10.1111/j.1432-1033.1976.tb10006.x,

Publication Year  1976

PubMed ID  1245181,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.