SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04151

Signal sequence   MFWTRYAGASILLFFMLIRLGQL

Length  23

Organism  Cyprinus carpio (Common carp)

UniProt ID  P01221,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04151.cif

Structure  SPKB04151.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2748.38564

Aliphatic index  127.3913043

Isoelectric point  11.14762293

Charge (pH=7)   1.997127263

Topological polar surface area  946.89

Aromaticity  0.217391304

Average rotatable bonds  3.826086957

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  32

X logP energy  -1.23906

Hydropathy 



Literature Information


Title  The evolution of gonadotropins: some molecular data concerning a non-mammalian pituitary gonadotropin, the hormone from a teleost fish (Cyprinus carpio L.).

DOI  10.1016/s0300-9084(78)80704-4,

Publication Year  1977

PubMed ID  607993,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.