SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04136

Signal sequence   MGLEKSLILFPLFFLLLGWVQPSLG

Length  25

Organism  Mus musculus (Mouse)

UniProt ID  P00683,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04136.cif

Structure  SPKB04136.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2819.48384

Aliphatic index  152

Isoelectric point  6.408795646

Charge (pH=7)   -0.000535612

Topological polar surface area  906.8

Aromaticity  0.16

Average rotatable bonds  3.56

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  32

X logP energy  0.4601

Hydropathy 



Literature Information


Title  The amino acid sequence of mouse pancreatic ribonuclease. Extremely rapid evolutionary rates of the myomorph rodent ribonucleases.

DOI  10.1111/j.1432-1033.1979.tb13199.x,

Publication Year  1979

PubMed ID  556267,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.