SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04124

Signal sequence   MRSSYRVGNPIRFQPTNVVGLLLLSLVLSFMLVQS

Length  35

Organism  Cimex lectularius (Bed bug) (Acanthia lectularia)

UniProt ID  O96559,

Motif  1..35



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04124.cif

Structure  SPKB04124.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3936.73264

Aliphatic index  130.5714286

Isoelectric point  12.20420625

Charge (pH=7)   2.997123951

Topological polar surface area  1534.81

Aromaticity  0.085714286

Average rotatable bonds  3.657142857

Number of hydrogen bond donors  54

Number of hydrogen bond acceptors  52

X logP energy  -12.84069

Hydropathy 



Literature Information


Title  Purification, cloning, and expression of an apyrase from the bed bug Cimex lectularius. A new type of nucleotide-binding enzyme.

DOI  10.1074/jbc.273.46.30583,

Publication Year  1998

PubMed ID  9804829,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.