SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04123

Signal sequence   MGRFIFVSFGLLVVFLSLSGSEA

Length  23

Organism  Crotalus durissus terrificus (South American rattlesnake)

UniProt ID  O93427,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04123.cif

Structure  SPKB04123.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2476.95934

Aliphatic index  126.9565217

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  883.64

Aromaticity  0.173913043

Average rotatable bonds  3.47826087

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  31

X logP energy  -5.00233

Hydropathy 



Literature Information


Title  Platelet activation and signal transduction by convulxin, a C-type lectin from Crotalus durissus terrificus (tropical rattlesnake) venom via the p62/GPVI collagen receptor.

DOI  10.1074/jbc.272.21.13576,

Publication Year  1997

PubMed ID  9153205,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.