SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04122

Signal sequence   MGRFIFVSFGLLVLFLSLSGTGA

Length  23

Organism  Crotalus durissus terrificus (South American rattlesnake)

UniProt ID  O93426,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04122.cif

Structure  SPKB04122.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2432.94944

Aliphatic index  131.3043478

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  846.34

Aromaticity  0.173913043

Average rotatable bonds  3.391304348

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  30

X logP energy  -4.45713

Hydropathy 



Literature Information


Title  Platelet activation and signal transduction by convulxin, a C-type lectin from Crotalus durissus terrificus (tropical rattlesnake) venom via the p62/GPVI collagen receptor.

DOI  10.1074/jbc.272.21.13576,

Publication Year  1997

PubMed ID  9153205,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.