SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04121

Signal sequence   MKSSVPSLLIACLVMSLNSYTQQ

Length  23

Organism  Gloydius brevicaudus siniticus (Chinese mamushi) (Agkistrodon blomhoffii siniticus)

UniProt ID  O93233,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04121.cif

Structure  SPKB04121.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2514.00834

Aliphatic index  114.3478261

Isoelectric point  8.522939048

Charge (pH=7)   0.934864135

Topological polar surface area  991.63

Aromaticity  0.043478261

Average rotatable bonds  3.608695652

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  38

X logP energy  -10.6055

Hydropathy 



Literature Information


Title  Purification and characterization of three distinct types of phospholipase A2 inhibitors from the blood plasma of the Chinese mamushi, Agkistrodon blomhoffii siniticus.

DOI  10.1042/bj3250527,

Publication Year  1997

PubMed ID  9230137,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.