SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04114

Signal sequence   MKGISKILSASIALMKLENVYS

Length  22

Organism  Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)

UniProt ID  O76942,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04114.cif

Structure  SPKB04114.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2396.92934

Aliphatic index  128.6363636

Isoelectric point  10.11959379

Charge (pH=7)   1.998023906

Topological polar surface area  934.02

Aromaticity  0.045454545

Average rotatable bonds  3.863636364

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  35

X logP energy  -7.2662

Hydropathy 



Literature Information


Title  On proteins of the microsporidian invasive apparatus: complete sequence of a polar tube protein of Encephalitozoon cuniculi.

DOI  10.1046/j.1365-2958.1998.00975.x,

Publication Year  1998

PubMed ID  9723921,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.