General Information
SPKB ID SPKB04112
Signal sequence MAKNGLVICILVITLLLDQTTS
Length 22
Organism Homo sapiens (Human)
UniProt ID O75596,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04112.cif
Physicochemical Information
Molecular weight 2359.90844
Aliphatic index 172.7272727
Isoelectric point 6.160569088
Charge (pH=7) -0.063838966
Topological polar surface area 904.84
Aromaticity 0
Average rotatable bonds 3.636363636
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 33
X logP energy -6.5266
Hydropathy 
Literature Information
Title Matrilysin (MMP-7) cleaves C-type lectin domain family 3 member A (CLEC3A) on tumor cell surface and modulates its cell adhesion activity.
DOI 10.1002/jcb.22062,
Publication Year 2009
PubMed ID 19173304,
Patent ID NA,
