SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04111

Signal sequence   MGSCDRKALWALSFLLLLLGSSSVQG

Length  26

Organism  Rattus norvegicus (Rat)

UniProt ID  O70280,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04111.cif

Structure  SPKB04111.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2753.27004

Aliphatic index  123.8461538

Isoelectric point  8.545113874

Charge (pH=7)   0.936157722

Topological polar surface area  1076.07

Aromaticity  0.076923077

Average rotatable bonds  3.538461538

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  38

X logP energy  -9.82543

Hydropathy 



Literature Information


Title  Purification of a novel protein (ps20) from urogenital sinus mesenchymal cells with growth inhibitory properties in vitro.

DOI  10.1074/jbc.270.37.22058,

Publication Year  1995

PubMed ID  7665628,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.