SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04107

Signal sequence   MKSIFLSLSLLASATVGVLA

Length  20

Organism  Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)

UniProt ID  O60046,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04107.cif

Structure  SPKB04107.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2021.48634

Aliphatic index  161

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  743.39

Aromaticity  0.05

Average rotatable bonds  3.35

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  -5.636

Hydropathy 



Literature Information


Title  A novel type of FKBP in the secretory pathway of Neurospora crassa.

DOI  10.1016/s0014-5793(00)01901-3,

Publication Year  2000

PubMed ID  11034311,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.