SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04103

Signal sequence   MKLALALCAAFLLVVLVQA

Length  19

Organism  Schistocerca gregaria (Desert locust) (Gryllus gregarius)

UniProt ID  O46162,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04103.cif

Structure  SPKB04103.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1987.57624

Aliphatic index  195.2631579

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  656.23

Aromaticity  0.052631579

Average rotatable bonds  3.421052632

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  24

X logP energy  -0.2111

Hydropathy 



Literature Information


Title  Purification and characterization of a group of five novel peptide serine protease inhibitors from ovaries of the desert locust, Schistocerca gregaria.

DOI  10.1016/s0014-5793(97)01585-8,

Publication Year  1998

PubMed ID  9475173,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.