SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04102

Signal sequence   MLFSKVIAPAFILLGAASAAPGGLAPENASKR

Length  32

Organism  Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432) (Darling's disease fungus) (Histoplasma capsulatum)

UniProt ID  O42720,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04102.cif

Structure  SPKB04102.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3169.77584

Aliphatic index  107.1875

Isoelectric point  10.7890093

Charge (pH=7)   1.999166043

Topological polar surface area  1194.07

Aromaticity  0.0625

Average rotatable bonds  3.125

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  42

X logP energy  -10.59143

Hydropathy 



Literature Information


Title  Histoplasma acquisition of calcium and expression of CBP1 during intracellular parasitism.

DOI  10.1046/j.1365-2958.1998.00697.x,

Publication Year  1998

PubMed ID  9489665,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.