SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04101

Signal sequence   MRAPTTVRCSGRIQRARWRGFLPLVLALLMGTSHA

Length  35

Organism  Rattus norvegicus (Rat)

UniProt ID  O35806,

Motif  1..35



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04101.cif

Structure  SPKB04101.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3923.72344

Aliphatic index  94.85714286

Isoelectric point  12.80106694

Charge (pH=7)   6.026898807

Topological polar surface area  1595.25

Aromaticity  0.057142857

Average rotatable bonds  3.6

Number of hydrogen bond donors  61

Number of hydrogen bond acceptors  52

X logP energy  -15.20308

Hydropathy 



Literature Information


Title  Peptidomics for Studying Limited Proteolysis.

DOI  10.1021/acs.jproteome.5b00820,

Publication Year  2015

PubMed ID  26479776,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.