SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04095

Signal sequence   MRKKLFSLALIGIFGLVVTNFGTKVDA

Length  27

Organism  Enterococcus faecium (Streptococcus faecium)

UniProt ID  O30434,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04095.cif

Structure  SPKB04095.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2939.59574

Aliphatic index  126.2962963

Isoelectric point  11.07952224

Charge (pH=7)   2.997542371

Topological polar surface area  1100.96

Aromaticity  0.111111111

Average rotatable bonds  3.703703704

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  38

X logP energy  -6.58283

Hydropathy 



Literature Information


Title  Biochemical and genetic characterization of enterocin P, a novel sec-dependent bacteriocin from Enterococcus faecium P13 with a broad antimicrobial spectrum.

DOI  10.1128/aem.63.11.4321-4330.1997,

Publication Year  1997

PubMed ID  9361419,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.