SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04084

Signal sequence   SC

Length  2

Organism  Crotalus durissus cumanensis (South American rattlesnake)

UniProt ID  K9N7B7,

Motif  <1..2



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04084.cif

Structure  SPKB04084.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  208.23224

Aliphatic index  0

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  112.65

Aromaticity  0

Average rotatable bonds  2.5

Number of hydrogen bond donors  5

Number of hydrogen bond acceptors  5

X logP energy  -2.1948

Hydropathy 



Literature Information


Title  Snake venomics of the Central American rattlesnake Crotalus simus and the South American Crotalus durissus complex points to neurotoxicity as an adaptive paedomorphic trend along Crotalus dispersal in South America.

DOI  10.1021/pr9008749,

Publication Year  2010

PubMed ID  19863078,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.