SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04079

Signal sequence   MSSGGLLLLLGLLTLCAELTPVSS

Length  24

Organism  Micrurus tener tener (Texas coral snake)

UniProt ID  G9I929,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04079.cif

Structure  SPKB04079.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2388.90354

Aliphatic index  162.5

Isoelectric point  3.849962145

Charge (pH=7)   -1.062215294

Topological polar surface area  882.51

Aromaticity  0

Average rotatable bonds  3.25

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  34

X logP energy  -7.6816

Hydropathy 



Literature Information


Title  A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain.

DOI  10.1038/nature10607,

Publication Year  2011

PubMed ID  22094702,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.