SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04074

Signal sequence   MKTLFVFAVGIMLSMRASA

Length  19

Organism  Cupiennius salei (American wandering spider)

UniProt ID  G4V4F9,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04074.cif

Structure  SPKB04074.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2073.60104

Aliphatic index  107.8947368

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  735.73

Aromaticity  0.105263158

Average rotatable bonds  3.631578947

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  -4.23153

Hydropathy 



Literature Information


Title  Purification, cDNA structure and biological significance of a single insulin-like growth factor-binding domain protein (SIBD-1) identified in the hemocytes of the spider Cupiennius salei.

DOI  10.1016/j.ibmb.2011.08.003,

Publication Year  2011

PubMed ID  21888974,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.