SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04073

Signal sequence   MKQLKLTGFVIFFFFLTESLT

Length  21

Organism  Bos taurus (Bovine)

UniProt ID  G3MYZ3,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04073.cif

Structure  SPKB04073.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2511.06024

Aliphatic index  106.6666667

Isoelectric point  9.537300927

Charge (pH=7)   0.999169354

Topological polar surface area  858.67

Aromaticity  0.238095238

Average rotatable bonds  3.952380952

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -1.8982

Hydropathy 



Literature Information


Title  Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/alpha-albumin.

DOI  10.7554/eLife.11621,

Publication Year  2016

PubMed ID  26902720,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.