SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04066

Signal sequence   MNAKTLFVVFLIGMLVTEQVEA

Length  22

Organism  Vaejovis mexicanus (Mexican scorpion)

UniProt ID  F1AWB0,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04066.cif

Structure  SPKB04066.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2453.98094

Aliphatic index  132.7272727

Isoelectric point  4.258147297

Charge (pH=7)   -0.998760489

Topological polar surface area  901.68

Aromaticity  0.090909091

Average rotatable bonds  3.727272727

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  32

X logP energy  -4.1886

Hydropathy 



Literature Information


Title  Vejovine, a new antibiotic from the scorpion venom of Vaejovis mexicanus.

DOI  10.1016/j.toxicon.2010.10.008,

Publication Year  2011

PubMed ID  20969885,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.