SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04063

Signal sequence   MNYLILISFALLVITGVES

Length  19

Organism  Mesobuthus eupeus (Lesser Asian scorpion) (Buthus eupeus)

UniProt ID  E7D082,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04063.cif

Structure  SPKB04063.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2096.55294

Aliphatic index  179.4736842

Isoelectric point  3.849982713

Charge (pH=7)   -1.001090992

Topological polar surface area  748.43

Aromaticity  0.105263158

Average rotatable bonds  3.578947368

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -2.5396

Hydropathy 



Literature Information


Title  Evolutionary diversification of Mesobuthus alpha-scorpion toxins affecting sodium channels.

DOI  10.1074/mcp.M111.012054,

Publication Year  2012

PubMed ID  21969612,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.