SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04062

Signal sequence   MKIIFLVLMMILSEVYS

Length  17

Organism  Androctonus crassicauda (Arabian fat-tailed scorpion)

UniProt ID  E7BLC7,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04062.cif

Structure  SPKB04062.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2030.61324

Aliphatic index  171.7647059

Isoelectric point  6.402001171

Charge (pH=7)   -0.001386026

Topological polar surface area  652.93

Aromaticity  0.117647059

Average rotatable bonds  4.058823529

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  26

X logP energy  1.1724

Hydropathy 



Literature Information


Title  Purification and cDNA cloning of a novel neurotoxic peptide (Acra3) from the scorpion Androctonus crassicauda.

DOI  10.1016/j.peptides.2012.07.009,

Publication Year  2012

PubMed ID  22819772,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.