SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04055

Signal sequence   MKILSIVLIALIICSISICTEA

Length  22

Organism  Mesobuthus eupeus (Lesser Asian scorpion) (Buthus eupeus)

UniProt ID  D3JXM1,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04055.cif

Structure  SPKB04055.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2347.99894

Aliphatic index  199.5454545

Isoelectric point  6.13535235

Charge (pH=7)   -0.124485044

Topological polar surface area  818.66

Aromaticity  0

Average rotatable bonds  3.636363636

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -3.2999

Hydropathy 



Literature Information


Title  Molecular divergence of two orthologous scorpion toxins affecting potassium channels.

DOI  10.1016/j.cbpa.2011.03.027,

Publication Year  2011

PubMed ID  21466856,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.