SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04054

Signal sequence   MGRFIFVSFGLLVVFLSLSGTGA

Length  23

Organism  Protobothrops jerdonii (Jerdon's pitviper) (Trimeresurus jerdonii)

UniProt ID  D1MGU0,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  3BX4,

Predicted Structure ID  SPKB04054.cif

Structure  SPKB04054.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2418.92264

Aliphatic index  126.9565217

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  846.34

Aromaticity  0.173913043

Average rotatable bonds  3.347826087

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  30

X logP energy  -4.84723

Hydropathy 



Literature Information


Title  A novel platelet glycoprotein Ib-binding protein with human platelet aggregation-inhibiting activity from Trimeresurus jerdonii venom.

DOI  10.1016/j.toxicon.2011.01.010,

Publication Year  2011

PubMed ID  21256857,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.