SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04051

Signal sequence   MKFQYLLAVFLIVLVVTDHCQA

Length  22

Organism  Isometrus maculatus (Lesser brown scorpion) (Scorpio maculatus)

UniProt ID  C7B247,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04051.cif

Structure  SPKB04051.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2552.13114

Aliphatic index  150.4545455

Isoelectric point  7.355480856

Charge (pH=7)   0.02621971

Topological polar surface area  893.06

Aromaticity  0.136363636

Average rotatable bonds  3.727272727

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -1.9287

Hydropathy 



Literature Information


Title  Complete de novo sequencing of antimicrobial peptides in the venom of the scorpion Isometrus maculatus.

DOI  10.1016/j.toxicon.2017.09.010,

Publication Year  2017

PubMed ID  28941793,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.