SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04050

Signal sequence   MRVSVPVLALAFGSLAAA

Length  18

Organism  Coccidioides posadasii (strain C735) (Valley fever fungus)

UniProt ID  C5P3X6,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04050.cif

Structure  SPKB04050.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1773.16694

Aliphatic index  141.1111111

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  651.59

Aromaticity  0.055555556

Average rotatable bonds  3

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  23

X logP energy  -4.77303

Hydropathy 



Literature Information


Title  A metalloproteinase of Coccidioides posadasii contributes to evasion of host detection.

DOI  10.1128/IAI.73.10.6689-6703.2005,

Publication Year  2005

PubMed ID  16177346,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.