SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04048

Signal sequence   MRVLLILVSLAALAHA

Length  16

Organism  Hyas araneus (Atlantic lyre crab) (Great spider crab)

UniProt ID  C4NZN9,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04048.cif

Structure  SPKB04048.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1691.15144

Aliphatic index  207.5

Isoelectric point  10.5517587

Charge (pH=7)   1.088890079

Topological polar surface area  610.63

Aromaticity  0

Average rotatable bonds  3.4375

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  21

X logP energy  -1.68703

Hydropathy 



Literature Information


Title  Hyastatin, a glycine-rich multi-domain antimicrobial peptide isolated from the spider crab (Hyas araneus) hemocytes.

DOI  10.1016/j.molimm.2009.05.002,

Publication Year  2009

PubMed ID  19487032,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.