SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04045

Signal sequence   MAAYLLAVAILFCIQGWPSGTVQG

Length  24

Organism  Bitis arietans (African puff adder)

UniProt ID  C0K3N1,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04045.cif

Structure  SPKB04045.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2510.00694

Aliphatic index  122.0833333

Isoelectric point  5.919503212

Charge (pH=7)   -0.064840831

Topological polar surface area  886.49

Aromaticity  0.125

Average rotatable bonds  3.166666667

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -4.9268

Hydropathy 



Literature Information


Title  Snake venom Vascular Endothelial Growth Factors (VEGF-Fs) exclusively vary their structures and functions among species.

DOI  10.1074/jbc.M809071200,

Publication Year  2009

PubMed ID  19208624,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.