SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04044

Signal sequence   MIYQVVLLLLVSPAPVSAA

Length  19

Organism  Trichonephila clavata (Joro spider) (Nephila clavata)

UniProt ID  C0HL38,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04044.cif

Structure  SPKB04044.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1984.46814

Aliphatic index  179.4736842

Isoelectric point  6.093198033

Charge (pH=7)   -0.002866115

Topological polar surface area  673.32

Aromaticity  0.052631579

Average rotatable bonds  3.105263158

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  25

X logP energy  -1.9972

Hydropathy 



Literature Information


Title  An insecticidal toxin from Nephila clavata spider venom.

DOI  10.1007/s00726-017-2425-2,

Publication Year  2017

PubMed ID  28497266,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.