SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04039

Signal sequence   MKISFLLLLALVICSIGWSEA

Length  21

Organism  Mesobuthus eupeus (Lesser Asian scorpion) (Buthus eupeus)

UniProt ID  C0HJQ8,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04039.cif

Structure  SPKB04039.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2307.87794

Aliphatic index  171.9047619

Isoelectric point  6.231833229

Charge (pH=7)   -0.062510328

Topological polar surface area  785.12

Aromaticity  0.095238095

Average rotatable bonds  3.619047619

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  29

X logP energy  -1.5894

Hydropathy 



Literature Information


Title  Variability of Potassium Channel Blockers in Mesobuthus eupeus Scorpion Venom with Focus on Kv1.1: AN INTEGRATED TRANSCRIPTOMIC AND PROTEOMIC STUDY.

DOI  10.1074/jbc.M115.637611,

Publication Year  2015

PubMed ID  25792741,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.