SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04038

Signal sequence   MKMFFTVLVTLFVCSMIIGICEG

Length  23

Organism  Mesobuthus eupeus (Lesser Asian scorpion) (Buthus eupeus)

UniProt ID  C0HJQ4,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04038.cif

Structure  SPKB04038.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2583.27704

Aliphatic index  122.6086957

Isoelectric point  6.13535235

Charge (pH=7)   -0.124485044

Topological polar surface area  827.53

Aromaticity  0.130434783

Average rotatable bonds  3.695652174

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  34

X logP energy  -1.8801

Hydropathy 



Literature Information


Title  Variability of Potassium Channel Blockers in Mesobuthus eupeus Scorpion Venom with Focus on Kv1.1: AN INTEGRATED TRANSCRIPTOMIC AND PROTEOMIC STUDY.

DOI  10.1074/jbc.M115.637611,

Publication Year  2015

PubMed ID  25792741,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.