General Information
SPKB ID SPKB04033
Signal sequence MRTLWIVAVCLMGVEG
Length 16
Organism Macrovipera lebetina transmediterranea (Blunt-nosed viper) (Vipera lebetina transmediterranea)
UniProt ID B5U6Z2,
Motif 1..16
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04033.cif
Physicochemical Information
Molecular weight 1778.21914
Aliphatic index 133.75
Isoelectric point 6.232433001
Charge (pH=7) -0.062218605
Topological polar surface area 635.04
Aromaticity 0.0625
Average rotatable bonds 3.5625
Number of hydrogen bond donors 24
Number of hydrogen bond acceptors 23
X logP energy -2.27183
Hydropathy
Literature Information
Title MVL-PLA2, a phospholipase A2 from Macrovipera lebetina transmediterranea venom, inhibits tumor cells adhesion and migration.
DOI 10.1016/j.matbio.2009.03.007,
Publication Year 2009
PubMed ID 19351557,
Patent ID NA,