SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04032

Signal sequence   MRALWIVAVWLIGVEG

Length  16

Organism  Echis ocellatus (Ocellated saw-scaled viper)

UniProt ID  B5U6Y4,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04032.cif

Structure  SPKB04032.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1813.23404

Aliphatic index  164.375

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  630.6

Aromaticity  0.125

Average rotatable bonds  3.5

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  20

X logP energy  0.45447

Hydropathy 



Literature Information


Title  Cytotoxic activities of [Ser??]phospholipase A? from the venom of the saw-scaled vipers Echis ocellatus, Echis pyramidum leakeyi, Echis carinatus sochureki, and Echis coloratus.

DOI  10.1016/j.toxicon.2013.05.017,

Publication Year  2013

PubMed ID  23747272,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.