SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04022

Signal sequence   MAHLLLAVVAITLALSQSVFG

Length  21

Organism  Acarus siro (Flour mite) (Tyroglyphus farinae)

UniProt ID  B0KZK1,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04022.cif

Structure  SPKB04022.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2154.63904

Aliphatic index  171.9047619

Isoelectric point  7.550323994

Charge (pH=7)   0.08889339

Topological polar surface area  777.78

Aromaticity  0.047619048

Average rotatable bonds  3.285714286

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  -4.3576

Hydropathy 



Literature Information


Title  Enzymatic activity and immunoreactivity of Aca s 4, an alpha-amylase allergen from the storage mite Acarus siro.

DOI  10.1186/1471-2091-13-3,

Publication Year  2012

PubMed ID  22292590,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.