SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04017

Signal sequence   MSSGGLLLLLGLLTLWAELTPISG

Length  24

Organism  Daboia siamensis (Eastern Russel's viper) (Daboia russelii siamensis)

UniProt ID  A8Y7P1,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04017.cif

Structure  SPKB04017.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2455.97844

Aliphatic index  166.6666667

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  878.07

Aromaticity  0.041666667

Average rotatable bonds  3.291666667

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -4.8582

Hydropathy 



Literature Information


Title  Purification, characterization and molecular cloning of chymotrypsin inhibitor peptides from the venom of Burmese Daboia russelii siamensis.

DOI  10.1016/j.peptides.2013.02.009,

Publication Year  2013

PubMed ID  23428970,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.