SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04014

Signal sequence   MRFKNVKKTALMLAMFGMATSSNA

Length  24

Organism  Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)

UniProt ID  A5F7A4,

Motif  1..24



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1W0O,

Predicted Structure ID  SPKB04014.cif

Structure  SPKB04014.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2649.24134

Aliphatic index  61.25

Isoelectric point  11.92450937

Charge (pH=7)   3.997095887

Topological polar surface area  1039.68

Aromaticity  0.083333333

Average rotatable bonds  3.833333333

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  39

X logP energy  -10.34703

Hydropathy 



Literature Information


Title  Cloning and expression of the Vibrio cholerae neuraminidase gene nanH in Escherichia coli.

DOI  10.1128/jb.170.4.1495-1504.1988,

Publication Year  1988

PubMed ID  2832365,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.