SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04009

Signal sequence   MKTLIVAALFCTIGMALA

Length  18

Organism  Anisakis simplex (Herring worm)

UniProt ID  A1IKL2,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04009.cif

Structure  SPKB04009.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1867.39684

Aliphatic index  146.6666667

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  624.5

Aromaticity  0.055555556

Average rotatable bonds  3.388888889

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  25

X logP energy  -2.1933

Hydropathy 



Literature Information


Title  Isolation of Ani s 5, an excretory-secretory and highly heat-resistant allergen useful for the diagnosis of Anisakis larvae sensitization.

DOI  10.1007/s00436-008-1105-2,

Publication Year  2008

PubMed ID  18618144,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.