General Information
SPKB ID SPKB03981
Signal sequence MKTLLLTLVVVTIVCLDLGNS
Length 21
Organism Micrurus fulvius (Eastern coral snake) (Coluber fulvius)
UniProt ID U3FAE1,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03981.cif
Physicochemical Information
Molecular weight 2245.80474
Aliphatic index 185.2380952
Isoelectric point 6.160569088
Charge (pH=7) -0.063838966
Topological polar surface area 832.65
Aromaticity 0
Average rotatable bonds 3.571428571
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 31
X logP energy -5.0309
Hydropathy
Literature Information
Title Fulditoxin, representing a new class of dimeric snake toxins, defines novel pharmacology at nicotinic ACh receptors.
DOI 10.1111/bph.14954,
Publication Year 2020
PubMed ID 31877243,
Patent ID NA,