SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03975

Signal sequence   MIMLLMVGMLMAPCVGA

Length  17

Organism  Mus musculus (Mouse)

UniProt ID  Q9Z0L3,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03975.cif

Structure  SPKB03975.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1781.39794

Aliphatic index  137.6470588

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  520.13

Aromaticity  0

Average rotatable bonds  3.411764706

Number of hydrogen bond donors  18

Number of hydrogen bond acceptors  24

X logP energy  0.1556

Hydropathy 



Literature Information


Title  Otoconin-90, the mammalian otoconial matrix protein, contains two domains of homology to secretory phospholipase A2.

DOI  10.1073/pnas.95.26.15345,

Publication Year  1998

PubMed ID  9860971,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.