General Information
SPKB ID SPKB03970
Signal sequence MAPRTLWSCYLCCLLTAAAGA
Length 21
Organism Homo sapiens (Human)
UniProt ID Q9Y6C2,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03970.cif
Physicochemical Information
Molecular weight 2215.68954
Aliphatic index 98.0952381
Isoelectric point 8.041747906
Charge (pH=7) 0.811206426
Topological polar surface area 795.14
Aromaticity 0.095238095
Average rotatable bonds 3.095238095
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 31
X logP energy -6.25223
Hydropathy
Literature Information
Title Diagnostic Exome Sequencing Identifies a Novel Gene, EMILIN1, Associated with Autosomal-Dominant Hereditary Connective Tissue Disease.
DOI 10.1002/humu.22920,
Publication Year 2016
PubMed ID 26462740,
Patent ID NA,