SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03968

Signal sequence   MGTKAQVERKLLCLFILAILLCSLALG

Length  27

Organism  Homo sapiens (Human)

UniProt ID  Q9Y624,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03968.cif

Structure  SPKB03968.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2918.69404

Aliphatic index  166.2962963

Isoelectric point  8.821557977

Charge (pH=7)   1.875216611

Topological polar surface area  1054.71

Aromaticity  0.037037037

Average rotatable bonds  3.740740741

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  38

X logP energy  -4.67733

Hydropathy 



Literature Information


Title  Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

DOI  10.1038/nbt810,

Publication Year  2003

PubMed ID  12665801,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.