SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03962

Signal sequence   MYLSRFLSIHALWVTVSSVMQPYPLVWG

Length  28

Organism  Homo sapiens (Human)

UniProt ID  Q9Y2I2,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  3ZYJ,

Predicted Structure ID  SPKB03962.cif

Structure  SPKB03962.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3281.92414

Aliphatic index  114.6428571

Isoelectric point  9.174205036

Charge (pH=7)   1.087189251

Topological polar surface area  1138.3

Aromaticity  0.178571429

Average rotatable bonds  3.464285714

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  41

X logP energy  -4.05583

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.