SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03960

Signal sequence   MMGLSLASAVLLASLLSLHLGTA

Length  23

Organism  Homo sapiens (Human)

UniProt ID  Q9Y258,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03960.cif

Structure  SPKB03960.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2269.78624

Aliphatic index  165.6521739

Isoelectric point  7.550323994

Charge (pH=7)   0.08889339

Topological polar surface area  833.35

Aromaticity  0

Average rotatable bonds  3.260869565

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  32

X logP energy  -6.7469

Hydropathy 



Literature Information


Title  Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3.

DOI  10.1074/jbc.274.39.27975,

Publication Year  1999

PubMed ID  10488147,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.