General Information
SPKB ID SPKB03959
Signal sequence MLLRSKPALPPPLMLLLLGPLGPLSPGALPRPAQA
Length 35
Organism Homo sapiens (Human)
UniProt ID Q9Y251,
Motif 1..35
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03959.cif
Physicochemical Information
Molecular weight 3597.51124
Aliphatic index 134
Isoelectric point 12.51647815
Charge (pH=7) 2.997682643
Topological polar surface area 1206.98
Aromaticity 0
Average rotatable bonds 3
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 44
X logP energy -5.66996
Hydropathy 
Literature Information
Title Biochemical characterization of the active heterodimer form of human heparanase (Hpa1) protein expressed in insect cells.
DOI 10.1042/BJ20030318,
Publication Year 2003
PubMed ID 12713442,
Patent ID NA,
