SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03953

Signal sequence   MKNLKKAAAVTMVAGGLIAAGAGMASA

Length  27

Organism  Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)

UniProt ID  Q9X9Z2,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell wall

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03953.cif

Structure  SPKB03953.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2504.06264

Aliphatic index  98.14814815

Isoelectric point  11.10307074

Charge (pH=7)   2.997099198

Topological polar surface area  981.53

Aromaticity  0

Average rotatable bonds  3.185185185

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  37

X logP energy  -10.9471

Hydropathy 



Literature Information


Title  A novel class of secreted hydrophobic proteins is involved in aerial hyphae formation in Streptomyces coelicolor by forming amyloid-like fibrils.

DOI  10.1101/gad.264303,

Publication Year  2003

PubMed ID  12832396,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.