SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03951

Signal sequence   MLPFASCLPGSLLLWAFLLLLLGAASP

Length  27

Organism  Mus musculus (Mouse)

UniProt ID  Q9WVJ9,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03951.cif

Structure  SPKB03951.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2815.51074

Aliphatic index  159.2592593

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  870.03

Aromaticity  0.111111111

Average rotatable bonds  3.074074074

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  33

X logP energy  -0.8057

Hydropathy 



Literature Information


Title  A comparative analysis of the fibulin protein family. Biochemical characterization, binding interactions, and tissue localization.

DOI  10.1074/jbc.M611029200,

Publication Year  2007

PubMed ID  17324935,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.