SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03949

Signal sequence   MRALGGITLLLAVAICQG

Length  18

Organism  Drosophila melanogaster (Fruit fly)

UniProt ID  Q9VMD9,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03949.cif

Structure  SPKB03949.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1800.25104

Aliphatic index  162.7777778

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  683.24

Aromaticity  0

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  24

X logP energy  -4.88113

Hydropathy 



Literature Information


Title  Tiggrin, a novel Drosophila extracellular matrix protein that functions as a ligand for Drosophila alpha PS2 beta PS integrins.

DOI  10.1242/dev.120.7.1747,

Publication Year  1994

PubMed ID  7924982,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.