General Information
SPKB ID SPKB03948
Signal sequence MDLRKHLGLLTLLLVAVFAFYGRPADA
Length 27
Organism Drosophila melanogaster (Fruit fly)
UniProt ID Q9VH14,
Motif 1..27
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03948.cif
Physicochemical Information
Molecular weight 3001.62624
Aliphatic index 137.4074074
Isoelectric point 9.298811696
Charge (pH=7) 1.088634288
Topological polar surface area 1104.69
Aromaticity 0.111111111
Average rotatable bonds 3.555555556
Number of hydrogen bond donors 39
Number of hydrogen bond acceptors 37
X logP energy -4.37526
Hydropathy
Literature Information
Title Drosophila TIMP is a potent inhibitor of MMPs and TACE: similarities in structure and function to TIMP-3.
DOI 10.1021/bi035358x,
Publication Year 2003
PubMed ID 14567681,
Patent ID NA,